Meet the PULSEspencer Series dispense. discover. with every pulse.
Empower your lab with a system that combines space-saving design, modular flexibility, and unmatched versatility. With Analytik Jena’s proven expertise in liquid handling, the PULSEspencer Series ensures precision and confidence in every assay.
Workflow Simplification and Assay Miniaturization
The devices simplify assay preparation by reducing the need for manual pipetting and serial dilution steps.
Precise Ultra-Low Volume Non-Contact Dispensing
The PULSEspencer Series can dispense extremely small volumes (from 8 pL) directly into assay plates without contact, supporting applications down to single cell assays and workflows.
User-Friendly Software Wizards
The software provides an intuitive, step-by-step wizard for guided assay creation.
Smart Assay Optimization Tools
The software automatically optimizes plate layouts, e.g. through randomization and concentration distribution.
Compact Design and Modular Combination
The PULSEspencer devices have a space-saving design and can be flexibly combined with other devices for several workflows.
Controlled single-cell dispensing
The PULSEspencer RC enables controlled, reproducible workflows for streamlined assays and single-cell omics applications.
Designed for precision reagent dispensing, the PULSEspencer Series streamlines complex workflows and supports assay miniaturization with ease. Covering volumes from picoliters to microliters, it offers unmatched flexibility for a wide range of applications. Whether you are preparing dilution series, optimizing conditions, or handling critical reagents, this system delivers accuracy and reproducibility in every step, saving time and resources in your lab. Its intuitive software guides you effortlessly through setup and operation, ensuring confidence, and efficiency from start to finish.
![[Translate to English (US):] Two lab assistants male and female on computer with PULSEspencer R](/fileadmin/_processed_/0/a/csm_IMG_PULSEspencer_series_09_2000px_f101e69384.jpg "Two lab assistants male and female on computer with PULSEspencer R")
Your lab benefits
Assay miniaturization
Consistent, high-quality data
Low volume consumption
Reduced contamination risk and variability
Save lab space and increase throughput
Minimal training and easy implementation
Redefine your assays Miniaturization meets precision – simplify workflows, save time, and achieve reliable results with every pulse.
Simplify complex workflows and reduce assay volumes without compromising accuracy. By reducing manual pipetting and serial dilution steps, the PULSEspencer series streamlines assay preparation and enables true miniturization. This means faster setup, lower reagent consumption, and consistent, reproducible results – all in a compact, high-tech solution.
Workflow Simplification and Assay Miniaturization
The devices simplify assay preparation by reducing the need for manual pipetting and serial dilution steps.
Your advantages
|
|
| Feature | PULSEspencer R | PULSEspencer RC |
|---|---|---|
| Dispensing Technology | Non-contact by applying thermally generated pressure pulses | |
| Volume Range | 8 pL – 200 μL* (approx. 7.4 orders of magnitude) | |
| Precision | < 8%** | |
| Compatibility | Reagents | Reagents and cell suspension |
| Dispensing Speed | Reagent: 10 nL across 96-well format in 20 sec, 10 nL across 384-well format in 70 sec | |
* depending on type of fluid and dispensehead cassette
** for volumes >100 pL
Precise ultra-low volume non-contact dispensing
The PULSEspencer Series can dispense extremely small volumes (from 8 pL) directly into assay plates without contact, supporting applications down to the level of single cell assays and workflows.
Your advantages
|
|
Achieve unmatched precision with ultra-low volume dispensing starting at just 8 picoliters – completely contact-free. The PULSEspencer Series delivers accurate droplets directly into assay plates, minimizing contamination risk and ensuring reliable performance for even the most demanding applications. Precision redefined for modern laboratories.
Ideal for Applications in:
- Drug Discovery and High-Throughput Screening
- Genomics and Proteomics
- Cell-Based Assays
- Biochemical Assays and Enzyme Studies
- Synthetic Biology and CRISPR Workflows
- Multiplex Assays
- Single-cell omics (PULSEspencer RC)
Cassettes for PULSEspencer R
| Cassette type | RR8 | RR4 | RR8s | RR4s |
|---|---|---|---|---|
| Description | 8 dispenseheads | 4 dispenseheads | 8 dispenseheads | 4 dispenseheads |
| Dispensing volume range | 8 pL - 20 μL | 1 nL - 200 μL | 11 pL - 20 μL | 1 nL - 200 μL |
| Compatibility | Aqueous solutions, protein | DMSO, >10 different PCR Master Mixes, aqueous solutions | ||
| Key capabilities | Titration low volume | Normalization | Titration low volume | Normalization |
Cassettes for PULSEspencer RC
| Cassette type | CC | CRL | CRH | CRLs | CRHs |
|---|---|---|---|---|---|
| Description | 1 dispensehead | ||||
| Dispensing volume range | 480 pL - 20 µL | 8 pL - 20 µL | 1 nL - 200 µL | 11 pL - 20 µL | 1 nL - 200 µL |
| Compatibility | Cell suspension | Aqueous solutions, protein | DMSO, acetonitrile*, >10 different PCR Master Mixes, aqueous solutions requiring surfactant | ||
| Key capabilities | Isolation of 1 to 25 cells per well | Titration low volume | Normalization | Titration low volume | Normalization |
* Only for CRLs cassettes
Intelligent tools for confident assay optimization The Analytik Jena dispenser software wizards and optimization tools simplify complex workflows, guide every step, and ensure reproducible results – enabling faster, more reliable assay development.
User-Friendly Software Wizards
The software provides an intuitive, step-by-step wizard for guided assay creation.
Your advantages
|
|
Start confidently with user-friendly software wizards that walk you through assay creation step by step. Whether setting up PCR- or titration assays, or synergistic studies, the system reduces complexity and minimizes errors, making even advanced workflows accessible to all users. Beyond guided workflows, the software actively optimizes plate layouts for maximum efficiency. It supports randomization of sample positions, auto-setup of dilution series based on minimum and maximum volumes or concentrations, and intelligent distribution of concentrations across wells. These tools minimize trial-and-error, improve reproducibility, and accelerate assay development, giving users confidence in every result.
A special simulation mode enables safe, test-based protocol setup prior to execution, reducing risks and saving reagents.
Smart assay optimization tools
The software automatically optimizes plate layouts, e.g. through randomization and normalization.
Tutorial videos PULSEspencer R
Device setup and software installation
In this tutorial, you will learn how to set up the device, install the software, and connect the system to get ready for your first experiments.
Plate alignment
In this tutorial, you will learn how to perform an A1 plate alignment on the PULSEspencer R to ensure precise and accurate dispensing. The video guides you through the alignment process, helping you quickly verify and fine tune the dispense position after moving the device or changing setups.
Setting up a new protocol
In this tutorial, you will learn how to set up a new protocol using the Analytik Jena dispenser software, including selecting plate formats, defining fluids, and applying templates such as titration. The video also shows how to simulate the protocol to check required cassettes and volumes before running experiments.
Running a protocol
In this tutorial, you will learn how to run a prepared protocol using the Analytik Jena dispenser software, including loading plates and cassettes, pipetting reagents, and following the guided dispensing steps. The video also shows how to review the run summary and access report files for full traceability.
Cassette types and selection
In this tutorial, you will get an overview of the available cassettes, their volume ranges, and their compatibility with surfactant and surfactant free fluids. The video explains how to choose the correct cassette type to ensure reliable and accurate dispensing for your experiments.
Intelligent Wizards Helping You Work Smarter and Error-Free
Titration
Create precise dilution series for accurate dose-response and optimization.
Randomization
Eliminate bias with smart sample randomization for reliable, reproducible results.
Synergy
Design powerful combination layouts to uncover synergistic or antagonistic effects.
Controlled single-cell dispensing
The PULSEspencer RC enables controlled, reproducible workflows for streamlined assays and single-cell omics applications.
Cell isolation
Assign an exact number of 1–25 cells per well for reliable and reproducible single cell analysis.
Compact, Modular — Expertly Engineered for Every Application The PULSEspencer Series combines a space-saving, modular design with unmatched application versatility. With decades of liquid handling expertise from Analytik Jena, they deliver precision and flexibility in any lab environment.
Compact Design and Modular Combination
The PULSEspencer devices have a space-saving design and can be flexibly combined with other devices for several workflows.
Your advantages
|
|
The PULSEspencer Series delivers high performance in a minimal footprint, freeing up valuable bench space without compromise. Its modular architecture scales effortlessly with evolving workflows, ensuring future-proof flexibility for applications ranging from drug discovery to genomics. Backed by Analytik Jena’s proven liquid handling expertise, it combines reliability, versatility, and space efficiency in one expertly engineered solution.
| Feature | PULSEspencer R | PULSEspencer RC |
|---|---|---|
| Dimensions (L x W x H) | 470 mm x 380 mm x 230 mm | 385 mm x 280 mm x 190 mm |
| Weight | 16.1 kg (35.4 lb) | 4.8 kg (10.58 lb) |
| Compatible labware | 12- to 1536-well plates (6-47 mm height)*, glass slides and custom labware | |
| Plate limits due to evaporation | DMSO: max. 32 plates, aqueous: max. 8 plates or 1536 wells | DMSO: max. 32 plates, aqueous: max. 8 plates or 1536 wells, acetonitrile: max. 100 wells across no more than 4 plates, cell fluid: max. 8 plates or 1536 wells |
Order Information
| Order number | Product | Compatible fluids | Packing unit(s) |
|---|---|---|---|
| 875-300010 | PULSEspencer R | ||
| 875-150010 | PULSEspencer RC | ||
| 875-300725 | PULSEspencer R Cassettes RR8 | Surfactant-free aqueous solutions and protein | 20 |
| 875-300720 | PULSEspencer R Cassettes RR8s | DMSO, >10 different PCR Master Mixes, aqueous solutions requiring surfactant | 20 |
| 875-300745 | PULSEspencer R Cassettes RR4 | Surfactant-free aqueous solutions and protein | 20 |
| 875-300740 | PULSEspencer R Cassettes RR4s | DMSO, >10 different PCR Master Mixes, aqueous solutions requiring surfactant | 20 |
| 875-150760 | PULSEspencer RC Cassettes CC | Cell suspension | 20 |
| 875-150725 | PULSEspencer RC Cassettes CRL | Surfactant-free aqueous solutions and protein | 30 |
| 875-150720 | PULSEspencer RC Cassettes CRLs | DMSO, acetonitrile, >10 different PCR Master Mixes, aqueous solutions requiring surfactant | 30 |
| 875-150745 | PULSEspencer RC Cassettes CRH | Surfactant-free aqueous solutions and protein | 30 |
| 875-150740 | PULSEspencer RC Cassettes CRHs | DMSO, >10 different PCR Master Mixes, aqueous solutions requiring surfactant | 30 |
Downloads
Interested? Contact us!
The newsletter of Analytik Jena frequently keeps you posted about:
- News
- Trends and developments
- Events